Janar bayani
Ma'anar girma-bambance-bambancen 15 (GDF15), kuma aka sani da MIC-1, memba ne mai ɓoye na ma'aunin girma mai canzawa (TGF) -β superfamily, a matsayin sabon abu mai sarrafa hypertrophic a cikin zuciya.GDF-15 / GDF15 ba a bayyana shi a cikin zuciyar manya na al'ada ba amma an jawo shi don mayar da martani ga yanayin da ke inganta hypertrophy da dilated cardiomyopathy kuma an bayyana shi sosai a cikin hanta.GDF-15 / GDF15 yana da tasiri wajen daidaita hanyoyin kumburi da apoptotic a cikin kyallen takarda da suka ji rauni da kuma lokacin tafiyar matakai na cututtuka.GDF-15 / GDF15 an haɗa su azaman ƙwayoyin ƙima waɗanda aka sarrafa su a wani wurin tsagewa don sakin wuraren C-terminal wanda ke ɗauke da sifa na 7 da aka kiyaye cystein a cikin balagagge furotin.GDF-15/GDF15 wuce gona da iri da ya taso daga faɗuwar rukunin erythroid yana ba da gudummawa ga hawan ƙarfe a cikin cututtukan thalassaemia ta hanyar hana bayyanar hepcidin.
Biyu Shawarwari | CLIA (Gano-Gano): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
Tsafta | > 95%, SDS-PAGE ya ƙaddara |
Tsarin Buffer | PBS, pH7.4. |
Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Sunan samfur | Cat.A'a | Clone ID |
GDF-15 | AB0038-1 | 3A2-1 |
AB0038-2 | 23F1-5 | |
AB0038-3 | 6C1-9 | |
AB0038-4 | 4D5-8 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
1.Wollert KC , Kempf T , Peter T , et al.Ƙimar Hasashen Girman-Bambancin Factor-15 a cikin Marasa lafiya Tare da Marasa Ƙaddamar da Ciwon Ciwon Ciwon Jiki [J].Zagayawa, 2007, 115 (8): 962-971.
2.Kempf T, Haehling SV, Peter T, et al.Amfanin haɓakar haɓakar haɓakar haɓaka-15 a cikin marasa lafiya tare da gazawar zuciya na yau da kullun.[J].Jaridar Cibiyar Nazarin Zuciya ta Amirka, 2007, 50 (11): 1054-1060.