Tsarin maganganun kwayar halitta na mammalian yana ɗaukar ƙwayoyin dabbobi masu shayarwa kamar HEK293 da CHO kuma yana ba da damar gyare-gyaren bayan fassarorin, gami da nadawa da hadaddun glycosylation, yana haifar da sunadaran da suka yi kama da takwarorinsu na dabi'a ta fuskar aiki.Sakamakon wannan fa'ida ta musamman, tsarin bayyanar da kwayoyin halitta na dabbobi masu shayarwa suna taka muhimmiyar rawa wajen gano kwayoyin halitta, tsarin gina jiki da bincike na aiki, da ci gaban injiniyan kwayoyin halitta.Koyaya, tsarin maganganun kwayar halitta na dabbobi masu shayarwa na yanzu yana da ƙayyadaddun ƙayyadaddun ƙayyadaddun lokaci, kamar dogon lokacin juyawa da tsadar samarwa.