Anti-mutum IGFBP-1 Antibody, Mouse Monoclonal
Bayanin samfur
Janar bayani
IGFBP1, wanda kuma aka sani da IGFBP-1 da kuma insulin-kamar haɓakar haɓakar furotin mai ɗaure 1, memba ne na dangin furotin mai haɓaka-kamar haɓakar insulin.IGF daurin sunadaran (IGFBPs) sunadaran sunadarai ne na 24 zuwa 45 kDa.Duk shida IGFBPs raba 50% homology kuma suna da alaƙa alaƙa ga IGF-I da IGF-II a daidai wannan tsari na girma kamar yadda ligands ke da IGF-IR.IGF-dauri sunadaran suna tsawaita rabin rayuwar IGFs kuma an nuna su ko dai hanawa ko haɓaka tasirin haɓakar haɓakar IGF akan al'adar tantanin halitta.Suna canza hulɗar IGFs tare da masu karɓa na sararin samaniya.IGFBP1 yana da yanki na IGFBP da yankin nau'in thyroglobulin-I.Yana ɗaure duka abubuwan haɓaka masu kama da insulin (IGFs) I da II kuma yana yawo a cikin plasma.Haɗin wannan furotin yana tsawaita rabin rayuwar IGFs kuma yana canza hulɗar su tare da masu karɓar sararin samaniya.
Kayayyaki
| Biyu Shawarwari | CLIA (Gano-Gano): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Tsafta | > 95% kamar yadda SDS-PAGE ya ƙaddara. |
| Tsarin Buffer | 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4 |
| Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Kwatancen Gasa
| Bioantibody | Cutar da aka gano ta asibiti | Jimlar | |
| M | Korau | ||
| M | 35 | 0 | 35 |
| Korau | 1 | 87 | 88 |
| Jimlar | 36 | 87 | 123 |
| Musamman | 100% | ||
| Hankali | 97% | ||
Bayanin oda
| Sunan samfur | Cat.A'a | Clone ID |
| Farashin IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
ambato
1.Rutanen EM .Insulin-kamar haɓakar haɓakar furotin 1: US 1996.
2.Harman, S, Mitchell, et al.Matakan Serum na Insulin-Kamar Ci gaban Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, da Prostate-Specific Antigen a matsayin Masu tsinkaya na Ciwon Ciwon Prostate na Clinical[J].Jaridar Clinical Endocrinology & Metabolism, 2000.
