Janar bayani
Interleukin-6 (IL-6) wani nau'in cytokine na α-helical ne mai yawa wanda ke daidaita haɓakar tantanin halitta da bambance-bambancen kyallen takarda, wanda aka sani musamman don rawar da yake takawa a cikin martanin rigakafi da halayen lokaci mai ƙarfi.Ana ɓoye furotin IL-6 ta nau'ikan tantanin halitta iri-iri ciki har da ƙwayoyin T da macrophages a matsayin ƙwayoyin phosphorylated da variably glycosylated.Yana aiwatar da ayyuka ta hanyar mai karɓa na heterodimeric wanda ya ƙunshi IL-6R wanda ba shi da yankin tyrosine / kinase kuma yana ɗaure IL-6 tare da ƙarancin alaƙa, kuma a ko'ina ya bayyana glycoprotein 130 (gp130) wanda ke ɗaure IL-6.IL-6R hadaddun tare da babban alaƙa kuma don haka yana canza sigina.IL-6 kuma yana shiga cikin hematopoiesis, metabolism na kashi, da ci gaban ciwon daji, kuma an ayyana shi azaman muhimmiyar rawa wajen jagorantar sauye-sauye daga asali zuwa rigakafi da aka samu.
Biyu Shawarwari | CLIA (Gano-Gano): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
Tsafta | > 95%, SDS-PAGE ya ƙaddara |
Tsarin Buffer | PBS, pH7.4. |
Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Sunan samfur | Cat.A'a | Clone ID |
IL6 | AB0001-1 | 1B1-4 |
AB0001-2 | 2E4-1 | |
AB0001-3 | 2C3-1 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
1.Zhong Z, Darnell ZW, Jr. Stat3: wani memba na STAT da aka kunna ta hanyar tyrosine phosphorylation don mayar da martani ga haɓakar haɓakar epidermal da interleukin-6 [J].Kimiyya, 1994.
2.J, Bauer, F, et al.Interleukin-6 a cikin maganin asibiti [J].Annals of Hematology, 1991.