Anti-human MPO Antibody, Mouse Monoclonal

Janar bayani
MPO (myeloperoxidase) wani enzyme ne na peroxidase wanda aka ɓoye ta hanyar leukocytes da aka kunna wanda ke taka rawa a cikin cututtuka na zuciya da jijiyoyin jini, musamman ta hanyar farawa da rashin aiki na endothelial.Myeloperoxidase (MPO) wani muhimmin enzyme ne, wanda shine daya daga cikin sassan tsarin kwayoyin cuta a cikin neutrophils da monocytes.MPO yana shiga cikin amsawar kumburi a wurare da yawa a cikin jiki, gami da mammary gland.Myeloperoxidase (MPO), wani takamaiman polymorphonuclear leukocyte enzyme, an yi amfani dashi a baya don ƙididdige adadin neutrophils a cikin nama.An gano aikin MPO yana da alaƙa da layi tare da adadin ƙwayoyin neutrophil.Tsarin MPO yana taka muhimmiyar rawa wajen kula da cututtuka da kuma share ƙwayoyin cuta.Duk da haka, sauye-sauye a cikin tsarin MPO na iya haifar da lalacewar DNA da carcinogenesis.Polymorphisms a cikin jinsin MPO an haɗa su tare da ƙara yawan magana na MPO da babban haɗari ga ci gaban ciwon daji.Myeloperoxidase (MPO) yana daya daga cikin manyan antigens na antineutrophil cytoplasmic autoantibodies (ANCA) da aka samu a cikin marasa lafiya da ƙananan vasculitis da Pauci-immune necrotizing glomerulonephritis.Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) wani autoantibody ne wanda ake samu akai-akai a cikin marasa lafiya tare da vasculitides.