Janar bayani
Pepsinogen I, madogarar pepsin, ana samar da shi ta mucosa na ciki kuma a sake shi cikin lumen na ciki da kuma wurare dabam dabam.Pepsinogen ya ƙunshi sarkar polypeptide guda ɗaya na amino acid 375 tare da matsakaicin nauyin kwayoyin 42 kD.PG I (isoenzyme 1-5) yana ɓoye musamman ta manyan sel a cikin mucosa na fundic, yayin da PG II (isoenzyme 6-7) ke ɓoye ta glandan pyloric da mucosa na duodenal na kusa.
Precursor yana nuna lambobi na ƙwayoyin saman ciki da kuma ƙwayoyin glandular, kuma yana sa ido kan atrophy na ciki a kaikaice.Hakanan suna da kwanciyar hankali sosai saboda suna gudanar da ayyukansu a ƙarƙashin yanayi mara kyau da ke cikin tsarin narkewar abinci.Atrophy na mucosa na corpus yana haifar da ƙananan kira na pepsinogen I kuma saboda haka ƙananan sakinsa a cikin jini.Serum pepsinogen I yana nuna aiki da jihohin mucosa na ciki.
Biyu Shawarwari | CLIA (Gano-Gano): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
Tsafta | > 95%, SDS-PAGE ya ƙaddara |
Tsarin Buffer | 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4 |
Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Sunan samfur | Cat.A'a | Clone ID |
PGI | AB0005-1 | 1C1-3 |
AB0005-2 | 1E3-1 | |
AB0005-3 | 1 G7-3 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
1.Sipponen P , Ranta P , Helske T , da dai sauransu.Matakan jini na gastrin-17 da pepsinogen I a cikin gastritis na atrophic: nazarin binciken kula da yanayin.[J].Jaridar Scandinavian na Gastroenterology, 2002, 37 (7): 785-791.
2.Mangla JC , Schenk EA , Desbaillets L , et al.Sirrin Pepsin, pepsinogen, da gastrin a cikin esophagus na Barrett.Halayen asibiti da ilimin halittar jiki[J].Gastroenterology, 1976, 70 (5 PT.1): 669-676.