Anti-Adamu PLGF Antibody, Mouse Monoclonal
Bayanin samfur
Janar bayani
Preeclampsia (PE) wani mawuyacin hali ne na ciki wanda ke nuna hauhawar jini da furotin bayan makonni 20 na ciki.Preeclampsia yana faruwa a cikin 3-5% na masu juna biyu kuma yana haifar da yawan mace-macen mata masu juna biyu da tayin ko na jarirai da rashin lafiya.Bayyanar cututtuka na iya bambanta daga m zuwa nau'i mai tsanani;preeclampsia har yanzu yana daya daga cikin manyan abubuwan da ke haifar da ciwon tayi da mata masu juna biyu da mace-mace.
Preeclampsia ya bayyana saboda sakin abubuwan angiogenic daga mahaifa wanda ke haifar da rashin aiki na endothelial.Matsakaicin matakan jini na PlGF (matsalolin haɓakar placental) da sFlt-1 (mai narkewa fms-kamar tyrosine kinase-1, wanda kuma aka sani da mai narkewa VEGF receptor-1) ana canza su a cikin mata masu fama da preeclampsia.Bugu da ƙari, matakan zagayawa na PlGF da sFlt-1 na iya ɓata ciki na al'ada daga preeclampsia tun kafin bayyanar cututtuka na asibiti ya faru.A cikin al'ada na ciki na al'ada, pro-angiogenic factor PlGF yana ƙaruwa a cikin farkon watanni biyu na farko kuma yana raguwa yayin da ciki ke ci gaba zuwa ƙarewa.Sabanin haka, matakan anti-angiogenic factor sFlt-1 sun kasance masu karko yayin farkon da tsakiyar matakan ciki kuma suna karuwa akai-akai har zuwa lokacin.A cikin matan da suka kamu da preeclampsia, an gano matakan sFlt-1 sun fi girma kuma an gano matakan PlGF sun yi ƙasa da na ciki na al'ada.
Kayayyaki
| Biyu Shawarwari | CLIA (Gano-Gano): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Tsafta | > 95% kamar yadda SDS-PAGE ya ƙaddara. |
| Tsarin Buffer | PBS, pH7.4. |
| Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Kwatancen Gasa
Bayanin oda
| Sunan samfur | Cat.A'a | Clone ID |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
ambato
1.Brown MA, Lindheimer MD, de Swiet M, et al.Rarraba da ganewar asali na cututtukan hawan jini na ciki: sanarwa daga Ƙungiyar Ƙasa ta Duniya don Nazarin hauhawar jini a cikin ciki (ISSHP).Ciwon Hawan Jini 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al.Pre-eclampsia: pathophysiology, ganewar asali, da gudanarwa.Vasc Health Risk Manag 2011;7:467-474.
