Protein Induced ta Vitamin K Rashi ko antagonist-II (PIVKA-II), wanda kuma aka sani da Des-γ-carboxy-prothrombin (DCP), wani nau'i ne na prothrombin mara kyau.Yawanci, ragowar prothrombin's 10 glutamic acid (Glu) a cikin yankin γ-carboxyglutamic acid (Gla) a matsayi 6, 7, 14, 16, 19, 20,25, 26, 29 da 32 suna γ-carboxylated zuwa Gla ta bitamin. -K dogara γ- glutamyl carboxylase a cikin hanta sannan kuma ya ɓoye cikin jini.A cikin marasa lafiya da ciwon hepatocellular carcinoma (HCC), γ-carboxylation na prothrombin yana lalacewa ta yadda PIVKA-II ya kasance a maimakon prothrombin.PIVKA-II ana la'akari da shi azaman ingantacciyar alamar halitta ta musamman don HCC.
Biyu Shawarwari | CLIA (Gano-Gano): 1E5 ~ 1D6 1E5 ~ 1E6 |
Tsafta | > 95%, SDS-PAGE ya ƙaddara |
Tsarin Buffer | 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4 |
Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa.Don ajiya na dogon lokaci, da fatan za a liquot ka adana shi.Guji maimaita daskarewa da narkewar hawan keke. |
Sunan samfur | Cat.A'a | Clone ID |
PIVKA-Ⅱ | AB0009-1 | 1F4 |
AB0009-2 | 1E5 | |
AB0009-3 | 1D6 | |
AB0009-4 | 1E6 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
1.Matsueda K , Yamamoto H , Yoshida Y , et al.Hepatoid carcinoma na pancreas yana samar da furotin wanda ya haifar da rashin bitamin K ko antagonist II (PIVKA-II) da α-fetoprotein (AFP) [J].Jaridar Gastroenterology, 2006, 41 (10): 1011-1019.
2.Viggiani, Valentina, Palombi, 等.Protein da aka jawo ta rashin bitamin K ko antagonist-II (PIVKA-II) ya karu musamman a cikin marasa lafiya na ciwon hanta na Italiyanci.[J].Jaridar Scandinavian na Gastroenterology, 2016.
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