Anti-human Her2 Antibody, Mouse Monoclonal
Bayanin samfur
Janar bayani
Mai karɓar haɓakar haɓakar haɓakar ɗan adam 2 (HER2), wanda kuma aka sani da ErbB2, NEU, da CD340, nau'in I membrane glycoprotein ne kuma yana cikin dangin mai karɓa na epidermal girma (EGF).Sunadaran HER2 ba zai iya ɗaure abubuwan haɓaka ba saboda ƙarancin yanki mai ɗaure ligand na kansa kuma an hana shi gabaɗaya.Duk da haka, HER2 yana samar da heterodimer tare da sauran dangin masu karɓa na EGF masu haɗin gwiwa, saboda haka yana daidaita haɗin haɗin ligand kuma yana haɓaka kunnawar kinase-mediated na ƙananan ƙwayoyin cuta.HER2 yana taka muhimmiyar rawa a ci gaba, yaduwar kwayar halitta da kuma bambanta.An ba da rahoton kwayar cutar HER2 tana haɗuwa da malignancy da rashin fahimta a yawancin carcinomas, ciki har da nono, prostate, ovarian, ciwon huhu da sauransu.
Kayayyaki
| Biyu Shawarwari | CLIA (Gano-Gano): 14-2~ 15-6 15-6~ 2-10 |
| Tsafta | > 95%, SDS-PAGE ya ƙaddara |
| Tsarin Buffer | PBS, pH7.4. |
| Adanawa | Ajiye shi a ƙarƙashin yanayin bakararre a -20 ℃ zuwa -80 ℃ lokacin karɓa. Na ba da shawarar a raba furotin zuwa ƙananan adadi don mafi kyawun ajiya. |
Bayanin oda
| Sunan samfur | Cat.A'a | Clone ID |
| Ita 2 | AB0078-1 | 14-2 |
| AB0078-2 | 15-6 | |
| AB0078-3 | 2-10 |
Lura: Bioantibody na iya keɓance adadi gwargwadon buƙatar ku.
ambato
1.Krawczyk N, et al.(2009) Matsayin HER2 akan ƙwayoyin ƙwayar ƙwayar cuta na ci gaba da yaduwa bayan maganin adjuvant na iya bambanta da matsayi na HER2 na farko akan ƙwayar cuta ta farko.Maganin ciwon daji Res.29 (10): 4019-24.
