Anti-Adamu CHI3L1 Antibody, ɗan adam Monoclonal

Janar bayani
Chitinase-3-like protein 1 (CHI3L1) wani ɓoye ne na heparin mai ɗaure glycoprotein wanda furcinsa yana da alaƙa da ƙaurawar ƙwayar tsoka mai santsi.An bayyana CHI3L1 a manyan matakai a cikin al'adun VSMC na nodular postconfluent kuma a ƙananan matakan a cikin al'adu masu yaduwa.CHI3L1 shine ƙuntataccen ƙwayar nama, lectin mai ɗaure chitin da memba na dangin glycosyl hydrolase 18. Ya bambanta da sauran alamomin monocyto / macrophage da yawa, maganganunsa ba ya nan a cikin monocytes kuma yana haifar da karfi a lokacin ƙarshen matakai na bambancin macrophage na mutum.Matsakaicin matakan CHI3L1 suna da alaƙa da rashin lafiya da ke nuna ƙarar jujjuyawar nama, irin su rheum atoid, amosanin gabbai, osteoarthritis, scleroderma, da cirrhosis na hanta, amma ana samarwa a cikin guringuntsi daga tsofaffin masu ba da gudummawa ko marasa lafiya tare da osteoarthritis.CHI3L1 an bayyana shi ba daidai ba a cikin hippocampus na batutuwa tare da schizophrenia kuma yana iya shiga cikin amsawar salula ga al'amuran muhalli daban-daban waɗanda aka ruwaito don ƙara haɗarin schizophrenia.